Persecution.

"Let us not be shocked by the suggestion that there are disadvantages
to the life in Christ. There most certainly are. Abel was murdered,
Joseph was sold into slavery, Daniel was thrown into the den of lions,
Stephen was stoned to death, Paul was beheaded, and a noble army of
martyrs was put to death by various painful methods all down the long
centuries. And where the hostility did not lead to such violence (and
mostly it did not and does not) the sons of this world nevertheless
managed to make it tough for the children of God in a thousand cruel
ways."
- A. W. Tozer